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Viral replication

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  • Viruses can only replicate inside viable host cells.
  • General strategy is to use the host cell enzymes to replicate and translate viral DNA, therefore making new virus particles, which burst out of the cell.
  • There are two main mechanisms

Mechanism 1Edit

  • The virus attaches to the host cell membrane. This stimulates endocytosis.
  • The viral envelope fuses with the vesicle membrane, releasing the nucleocapsids into the cytoplasm.
  • The viral RNA from this enters the nucleus, where it is replicated to form mRNA using the viral RNA polymerase enzyme.

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